![]() ![]() When the treasonous behavior and extramarital affairs of Isabella's sister-in-law Leonora became a symbol for the anarchy of Francesco's court, Francesco sanctioned Leonora's murder at her husband's hands and, soon after, Isabella's murder by her husband as well. After Cosimo's death in 1574, his spiteful eldest son and heir, Francesco, eager to make his mistress, the first lady of Florence, reneged on the inheritance Cosimo left Isabella and her children and effectively banished her lover from Florence by branding him a murderer. The third of eight surviving children, Isabella de' Medici (1542–1576) was unusually close to her father, Cosimo, the powerful grand duke of Tuscany who built the Uffizi, and whose protection allowed her to live an autonomous, glittering Florentine life apart from her debt-ridden, abusive, playboy husband in Rome. ![]()
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